Lighting the Way

Addressing unmet medical needs in orphan diseases

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Precise Targeting of Neuroinflammation/ Injured Microglia

Resources for Patients & Families

Single Dose Restores Normal Function in Neonatal Brain Injury Model

About Orpheris

Orpheris is focused on the treatment of neuroinflammatory orphan diseases that result in death or severe disabilities, including childhood cerebral adrenoleukodystrophy (ccALD), Parkinson's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, Rett syndrome and autism spectrum disorders. Orpheris' patented hydroxyl dendrimer technology selectively targets activated microglia implicated in a number of brain diseases.

Controlling neuroinflammation through targeting activated microglia with OP-101 is a potent weapon against CNS disorders. OP-101 is the company's first potential drug candidate utilizing hydroxyl dendrimer technology to deliver therapeutic doses of an anti-inflammatory drug across the blood brain barrier to reduce neuroinflammation.